Before you set up MSCS, review the list of functions that are not supported for this release, and requirements and recommendations that apply to your configuration.

The following environments and functions are not supported for MSCS setups with this release of vSphere:

Clustering on iSCSI, FCoE, and NFS disks.

Mixed environments, such as configurations where one cluster node is running a different version of ESXi than another cluster node.

Use of MSCS in conjunction with vSphere Fault Tolerance (FT).

Migration with vSphere vMotion® of clustered virtual machines.

N-Port ID Virtualization (NPIV)

With native multipathing (NMP), clustering is not supported when the path policy is set to round robin. Third-party multipathing plug-ins might support round robin or other load balancing behavior with Microsoft clusters. Support of third-party multipathing plug-ins is provided by the plug-in vendor.

ESXi hosts that use memory overcommitment are not suitable for deploying MSCS virtual machines. Memory overcommitment can cause virtual machines to stall for short durations. This can be significantly disruptive as the MSCS clustering mechanism is time-sensitive and timing delays can cause the virtual machines to behave incorrectly.