If your host has more than one physical NIC for iSCSI, for each physical NIC, create a separate iSCSI port using 1:1 mapping.

To achieve the 1:1 mapping, designate a separate vSwitch for each network adapter and iSCSI port pair. See iSCSI Ports and NICs on Separate vSwitches.

iSCSI Ports and NICs on Separate vSwitches
The graphic shows NIC and port pairs connected through separate vSwitches.

An alternative is to add all NIC and iSCSI port pairs to a single vSwitch. See iSCSI Ports and NICs on a Single vSwitch. You must override the default setup and make sure that each port maps to only one corresponding active NIC.

iSCSI Ports and NICs on a Single vSwitch
The graphic shows two physical NIC and iSCSI port pairs connected through a single vSwitch.

For information about adding the NIC and VMkernel port pairs to a vSwitch, see Create Additional iSCSI Ports for Multiple NICs.

After you map iSCSI ports to network adapters, use the esxcli command to bind the ports to the iSCSI adapters. With dependent hardware iSCSI adapters, perform port binding, whether you use one NIC or multiple NICs. For information, see Bind iSCSI Ports to iSCSI Adapters.