You can use multiple VMkernel adapters bound to iSCSI to have multiple paths to an iSCSI array that broadcasts a single IP address.

When you use port binding for multipathing, follow these guidelines:

iSCSI ports of the array target must reside in the same broadcast domain and IP subnet as the VMkernel adapters.

All VMkernel adapters used for iSCSI port binding must reside in the same broadcast domain and IP subnet.

All VMkernel adapters used for iSCSI connectivity must reside in the same virtual switch.

Port binding does not support network routing.

Do not use port binding when any of the following conditions exist:

Array target iSCSI ports are in a different broadcast domain and IP subnet.

VMkernel adapters used for iSCSI connectivity exist in different broadcast domains, IP subnets, or use different virtual switches.

Routing is required to reach the iSCSI array.