You might be able to improve the performance of the applications on a virtual machine by associating it to the CPU numbers on a single NUMA node (manual CPU affinity).

1

Using a vSphere Client, right-click a virtual machine and select Edit Settings.

2

In the Virtual Machine Properties dialog box, select the Resources tab and select Advanced CPU.

3

In the Scheduling Affinity panel, set CPU affinity for different NUMA nodes.

Note

You must manually select the boxes for all processors in the NUMA node. CPU affinity is specified on a per-processor, not on a per-node, basis.