The first step in setting up your vSphere environment is to create a datacenter.

If you are logging in for the first time, you should have no inventory items in the Inventory panel.

vCenter Server with No Inventory Objects and the First Step in the Getting Started Tab Wizard
vSphere Client connected to vCenter Server with no inventory objects with the Getting Started tab wizard open.
1

On the Getting Started tab in the Information panel, follow the on-screen instructions and click Create a datacenter.

This creates a datacenter.

2

Name the datacenter by selecting it and entering a name.

After you create a datacenter, add the ESX host to it.