You can use SRM to protect Microsoft Cluster Server (MSCS) and fault tolerant virtual machines, with certain limitations.

To protect MSCS or fault tolerant virtual machines, the host machines on which the virtual machines run must meet certain criteria.

You must run a fault tolerant virtual machine and its shadow on two separate ESXi Servers.

You can run a cluster of MSCS virtual machines in the following possible configurations.

Cluster-in-a-box

The MSCS virtual machines in the cluster run on a single ESXi Server. You can have a maximum of two MSCS virtual machines in the cluster.

Cluster-across-boxes

You can spread the MSCS cluster across a maximum of two ESXi Server instances. You can protect only one virtual machine node of any MSCS cluster on a single ESXi Server instance. You can have multiple MSCS node virtual machines running on an ESXi host, as long as they do not participate in the same MSCS cluster. When running MSCS in a cluster-across-boxes configuration, SRM only supports two-node MSCS clusters.

Reprotect of MSCS or fault tolerant virtual machines is impossible if you do not enable VMware High Availability (HA) and Distributed Resource Scheduler (DRS). When moving MSCS or fault tolerant virtual machines across their primary and secondary sites during reprotect, you must enable HA and DRS, setting the affinity and antiaffinity rules as appropriate.